INHBA (inhibin subunit beta A)

2003-06-01  

Identity

HGNC
INHBA
LOCATION
7p14.1
LOCUSID
3624
ALIAS
EDF,FRP

Other Information

Locus ID:

NCBI: 3624
MIM: 147290
HGNC: 6066
Ensembl: ENSG00000122641

Variants:

dbSNP: 3624
ClinVar: 3624
TCGA: ENSG00000122641
COSMIC: INHBA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122641ENST00000242208P08476
ENSG00000122641ENST00000242208A4D1W7
ENSG00000122641ENST00000442711P08476
ENSG00000122641ENST00000442711A4D1W7
ENSG00000122641ENST00000638023P08476
ENSG00000122641ENST00000638023A4D1W7

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
TGF-beta signaling pathwayKEGGko04350
Cytokine-cytokine receptor interactionKEGGhsa04060
TGF-beta signaling pathwayKEGGhsa04350
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Activin signalingKEGGhsa_M00681
Activin signalingKEGGM00681
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Peptide hormone biosynthesisREACTOMER-HSA-209952
Glycoprotein hormonesREACTOMER-HSA-209822
Signal TransductionREACTOMER-HSA-162582
Signaling by ActivinREACTOMER-HSA-1502540
Antagonism of Activin by FollistatinREACTOMER-HSA-2473224

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA130232992bevacizumabChemicalVariantAnnotationnot associatedPD29852030
PA164746012ranibizumabChemicalVariantAnnotationnot associatedPD29852030

References

Pubmed IDYearTitleCitations
382521482024FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression.0
383293862024INHBA is Enriched in HPV-negative Oropharyngeal Squamous Cell Carcinoma and Promotes Cancer Progression.0
384195622024Elevated INHBA Promotes Tumor Progression of Cervical Cancer.0
385318072024Inhibin A contributes to the tumorigenesis of oral squamous cell carcinoma by KIAA1429-mediated m6A modification.0
382521482024FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression.0
383293862024INHBA is Enriched in HPV-negative Oropharyngeal Squamous Cell Carcinoma and Promotes Cancer Progression.0
384195622024Elevated INHBA Promotes Tumor Progression of Cervical Cancer.0
385318072024Inhibin A contributes to the tumorigenesis of oral squamous cell carcinoma by KIAA1429-mediated m6A modification.0
356243272023CGB5, INHBA and TRAJ19 Hold Prognostic Potential as Immune Genes for Patients with Gastric Cancer.2
369844962023Correlation of INHBA Overexpression with Pathological Features, Antitumor Immune Response and Clinical Prognosis in Cervical Cancer.2
370977492023Impaired angiogenesis in diabetic critical limb ischemia is mediated by a miR-130b/INHBA signaling axis.1
375674362023ΔNp63 overexpression promotes oral cancer cell migration through hyperactivated Activin A signaling.0
380628042023The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer.1
356243272023CGB5, INHBA and TRAJ19 Hold Prognostic Potential as Immune Genes for Patients with Gastric Cancer.2
369844962023Correlation of INHBA Overexpression with Pathological Features, Antitumor Immune Response and Clinical Prognosis in Cervical Cancer.2

Citation

Dessen P

INHBA (inhibin subunit beta A)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40980/inhba-(inhibin-subunit-beta-a)