Identity
HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
SHIP,SHIP-1,SHIP1,SIP-145,hp51CN,p150Ship
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3635
MIM: 601582
HGNC: 6079
Ensembl: ENSG00000168918
Variants:
dbSNP: 3635
ClinVar: 3635
TCGA: ENSG00000168918
COSMIC: INPP5D
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38309262 | 2024 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. | 0 |
| 38613944 | 2024 | SHIP inhibition mediates select TREM2-induced microglial functions. | 0 |
| 38309262 | 2024 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. | 0 |
| 38613944 | 2024 | SHIP inhibition mediates select TREM2-induced microglial functions. | 0 |
| 36208705 | 2023 | Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants. | 1 |
| 36586275 | 2023 | SHIP1 is required for the formation of neutrophil extracellular traps in rheumatoid arthritis. | 0 |
| 36881903 | 2023 | Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1. | 2 |
| 36923408 | 2023 | CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression. | 2 |
| 36958526 | 2023 | Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021. | 2 |
| 36981033 | 2023 | Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer's Disease Neuropathology and Genetics. | 8 |
| 37108169 | 2023 | Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk. | 2 |
| 37207939 | 2023 | Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases. | 1 |
| 37895194 | 2023 | INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer's Disease Pathophysiology. | 1 |
| 38016942 | 2023 | INPP5D regulates inflammasome activation in human microglia. | 6 |
| 36208705 | 2023 | Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants. | 1 |
Citation
Dessen P
INPP5D (inositol polyphosphate-5-phosphatase D)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40983/inpp5d-(inositol-polyphosphate-5-phosphatase-d)
