IPO7 (importin 7)

2003-05-01  

Identity

HGNC
IPO7
LOCATION
11p15.4
LOCUSID
10527
ALIAS
Imp7,RANBP7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10527
MIM: 605586
HGNC: 9852
Ensembl: ENSG00000205339

Variants:

dbSNP: 10527
ClinVar: 10527
TCGA: ENSG00000205339
COSMIC: IPO7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205339ENST00000379719O95373
ENSG00000205339ENST00000527431E9PLB2
ENSG00000205339ENST00000533233E9PLJ0
ENSG00000205339ENST00000630083E9PLJ0

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386501272024Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma.0
386501272024Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma.0
355885772022IPO7 promotes pancreatic cancer progression via regulating ERBB pathway.0
355885772022IPO7 promotes pancreatic cancer progression via regulating ERBB pathway.0
334822492021The sequence [EKRKI(E/R)(K/L/R/S/T)] is a nuclear localization signal for importin 7 binding (NLS7).10
334822492021The sequence [EKRKI(E/R)(K/L/R/S/T)] is a nuclear localization signal for importin 7 binding (NLS7).10
315054352019Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation.2
315054352019Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation.2
273819822016Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.0
275286062016Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.28
273819822016Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.0
275286062016Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.28
260850852015Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.17
260850852015Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.17
245864282014Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.14

Citation

Dessen P

IPO7 (importin 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40987/ipo7-(importin-7)