FCRL4 (Fc receptor like 4)

2003-02-01 Affiliation

Identity

HGNC

FCRL4

LOCATION

1q23.1

LOCUSID

83417

ALIAS

CD307d,FCRH4,IGFP2,IRTA1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 83417
MIM: 605876
HGNC: 18507
Ensembl: ENSG00000163518

Variants:

dbSNP: 83417
ClinVar: 83417
TCGA: ENSG00000163518
COSMIC: FCRL4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000163518	ENST00000271532	Q96PJ5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34309899	2022	IRTA1 positivity helps identify a MALT-lymphoma-like subset of primary cutaneous marginal zone lymphomas, largely but not exclusively defined by IgM expression.	5
34309899	2022	IRTA1 positivity helps identify a MALT-lymphoma-like subset of primary cutaneous marginal zone lymphomas, largely but not exclusively defined by IgM expression.	5
34168653	2021	The Multiple Roles of B Cells in the Pathogenesis of Sjögren's Syndrome.	19
34168653	2021	The Multiple Roles of B Cells in the Pathogenesis of Sjögren's Syndrome.	19
32201227	2020	Gene expression profiling of epithelium-associated FcRL4(+) B cells in primary Sjögren's syndrome reveals a pathogenic signature.	22
32805738	2020	Fc receptor-like 4 and 5 define human atypical memory B cells.	9
32201227	2020	Gene expression profiling of epithelium-associated FcRL4(+) B cells in primary Sjögren's syndrome reveals a pathogenic signature.	22
32805738	2020	Fc receptor-like 4 and 5 define human atypical memory B cells.	9
30346478	2019	IRTA1 and MNDA Expression in Marginal Zone Lymphoma: Utility in Differential Diagnosis and Implications for Classification.	13
30346478	2019	IRTA1 and MNDA Expression in Marginal Zone Lymphoma: Utility in Differential Diagnosis and Implications for Classification.	13
29703863	2018	Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens.	6
29703863	2018	Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens.	6
27666766	2017	Immunohistochemical analysis of the novel marginal zone B-cell marker IRTA1 in malignant lymphoma.	9
28343748	2017	B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis.	30
28390747	2017	FcRL4(+) B-cells in salivary glands of primary Sjögren's syndrome patients.	19

Citation

Dessen P

FCRL4 (Fc receptor like 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40995/fcrl4-(fc-receptor-like-4)