Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8516
MIM: 604063
HGNC: 6144
Ensembl: ENSG00000077943
Variants:
dbSNP: 8516
ClinVar: 8516
TCGA: ENSG00000077943
COSMIC: ITGA8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000077943 | ENST00000378076 | P53708 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37119505 | 2024 | Hypermethylated ITGA8 Facilitate Bladder Cancer Cell Proliferation and Metastasis. | 1 |
| 37119505 | 2024 | Hypermethylated ITGA8 Facilitate Bladder Cancer Cell Proliferation and Metastasis. | 1 |
| 36089563 | 2023 | Bi-allelic pathogenic variants in ITGA8 cause slowly progressive renal disease of unknown etiology. | 1 |
| 36911684 | 2023 | LINC01798/miR-17-5p axis regulates ITGA8 and causes changes in tumor microenvironment and stemness in lung adenocarcinoma. | 6 |
| 36089563 | 2023 | Bi-allelic pathogenic variants in ITGA8 cause slowly progressive renal disease of unknown etiology. | 1 |
| 36911684 | 2023 | LINC01798/miR-17-5p axis regulates ITGA8 and causes changes in tumor microenvironment and stemness in lung adenocarcinoma. | 6 |
| 36088840 | 2022 | Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnion. | 2 |
| 36088840 | 2022 | Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnion. | 2 |
| 33433924 | 2021 | Induced hepatic stellate cell integrin, α8β1, enhances cellular contractility and TGFβ activity in liver fibrosis. | 14 |
| 33961857 | 2021 | ITGA8 positive cells in the conventional outflow tissue exhibit Schlemm's canal endothelial cell properties. | 1 |
| 33433924 | 2021 | Induced hepatic stellate cell integrin, α8β1, enhances cellular contractility and TGFβ activity in liver fibrosis. | 14 |
| 33961857 | 2021 | ITGA8 positive cells in the conventional outflow tissue exhibit Schlemm's canal endothelial cell properties. | 1 |
| 26198048 | 2016 | ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients. | 28 |
| 26198048 | 2016 | ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients. | 28 |
| 24439109 | 2014 | Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans. | 41 |
Citation
Dessen P
ITGA8 (integrin subunit alpha 8)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41009/itga8-(integrin-subunit-alpha-8)
