Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
CD103,HUMINAE
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3682
MIM: 604682
HGNC: 6147
Ensembl: ENSG00000083457
Variants:
dbSNP: 3682
ClinVar: 3682
TCGA: ENSG00000083457
COSMIC: ITGAE
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000083457 | ENST00000263087 | P38570 |
| ENSG00000083457 | ENST00000574026 | K7EQU0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38561495 | 2024 | Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. | 0 |
| 38781659 | 2024 | Cryo-EM structure of I domain-containing integrin αEβ7. | 0 |
| 38561495 | 2024 | Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. | 0 |
| 38781659 | 2024 | Cryo-EM structure of I domain-containing integrin αEβ7. | 0 |
| 35776160 | 2023 | The tissue-resident marker CD103 on peripheral blood T cells predicts responses to anti-PD-1 therapy in gastric cancer. | 9 |
| 36792124 | 2023 | CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden. | 10 |
| 35776160 | 2023 | The tissue-resident marker CD103 on peripheral blood T cells predicts responses to anti-PD-1 therapy in gastric cancer. | 9 |
| 36792124 | 2023 | CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden. | 10 |
| 34658046 | 2022 | CD103 integrin identifies a high IL-10-producing FoxP3(+) regulatory T-cell population suppressing allergic airway inflammation. | 4 |
| 36036450 | 2022 | The multifunctional nature of CD103 (αEβ7 integrin) signaling in tissue-resident lymphocytes. | 4 |
| 34658046 | 2022 | CD103 integrin identifies a high IL-10-producing FoxP3(+) regulatory T-cell population suppressing allergic airway inflammation. | 4 |
| 36036450 | 2022 | The multifunctional nature of CD103 (αEβ7 integrin) signaling in tissue-resident lymphocytes. | 4 |
| 33479027 | 2021 | CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma. | 12 |
| 33827905 | 2021 | Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade. | 57 |
| 34298400 | 2021 | The differentiation of new human CD303(+) Plasmacytoid dendritic cell subpopulations expressing CD205 and/or CD103 regulated by Non-Small-Cell lung cancer cells. | 1 |
Citation
Dessen P
ITGAE (integrin subunit alpha E)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41012/itgae-(integrin-subunit-alpha-e)
