Identity
HGNC
LOCATION
1q42.12
LOCUSID
ALIAS
IP3-3KB,IP3K,IP3K-B,IP3KB,PIG37
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3707
MIM: 147522
HGNC: 6179
Ensembl: ENSG00000143772
Variants:
dbSNP: 3707
ClinVar: 3707
TCGA: ENSG00000143772
COSMIC: ITPKB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143772 | ENST00000272117 | P27987 |
| ENSG00000143772 | ENST00000366784 | P27987 |
| ENSG00000143772 | ENST00000429204 | P27987 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38438346 | 2024 | Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis. | 1 |
| 38438346 | 2024 | Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis. | 1 |
| 36768321 | 2023 | Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status. | 1 |
| 37108169 | 2023 | Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk. | 2 |
| 36768321 | 2023 | Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status. | 1 |
| 37108169 | 2023 | Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk. | 2 |
| 34244037 | 2022 | Association of ITPKB, IL1R2 and COQ7 with Parkinson's disease in Taiwan. | 1 |
| 34244037 | 2022 | Association of ITPKB, IL1R2 and COQ7 with Parkinson's disease in Taiwan. | 1 |
| 31987846 | 2020 | Severe combined immunodeficiency caused by inositol-trisphosphate 3-kinase B (ITPKB) deficiency. | 3 |
| 31987846 | 2020 | Severe combined immunodeficiency caused by inositol-trisphosphate 3-kinase B (ITPKB) deficiency. | 3 |
| 31081803 | 2019 | Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. | 16 |
| 31081803 | 2019 | Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. | 16 |
| 29871874 | 2018 | Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells. | 4 |
| 29871874 | 2018 | Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells. | 4 |
| 27485122 | 2016 | miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. | 73 |
Citation
Dessen P
ITPKB (inositol-trisphosphate 3-kinase B)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41026
