JARID2 (jumonji and AT-rich interaction domain containing 2)

2003-05-01  

Identity

HGNC
LOCATION
6p22.3
LOCUSID
ALIAS
JMJ
FUSION GENES

Other Information

Locus ID:

NCBI: 3720
MIM: 601594
HGNC: 6196
Ensembl: ENSG00000008083

Variants:

dbSNP: 3720
ClinVar: 3720
TCGA: ENSG00000008083
COSMIC: JARID2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008083ENST00000341776Q92833
ENSG00000008083ENST00000397311Q92833

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
PRC2 methylates histones and DNAREACTOMER-HSA-212300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366406272023JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis.0
373095912023Integrated bioinformatics and experimental validation reveal the role of JARID2 in ovarian cancer.0
373530422023JARID2 and EZH2, the eminent epigenetic drivers in human cancer.4
377625462023Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature.1
366406272023JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis.0
373095912023Integrated bioinformatics and experimental validation reveal the role of JARID2 in ovarian cancer.0
373530422023JARID2 and EZH2, the eminent epigenetic drivers in human cancer.4
377625462023Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature.1
337893122022LINC00649 Facilitates the Cellular Process of Bladder Cancer Cells via Signaling Axis miR-16-5p/JARID2.4
342403232022microRNA-206 Suppresses Cholangiocarcinoma Cell Growth and Invasion by Targeting Jumonji AT-Rich Interactive Domain 2.1
351733092022LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.12
364712812022The LINC00852/miR-29a-3p/JARID2 axis regulates the proliferation and invasion of prostate cancer cell.4
337893122022LINC00649 Facilitates the Cellular Process of Bladder Cancer Cells via Signaling Axis miR-16-5p/JARID2.4
342403232022microRNA-206 Suppresses Cholangiocarcinoma Cell Growth and Invasion by Targeting Jumonji AT-Rich Interactive Domain 2.1
351733092022LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.12

Citation

Dessen P

JARID2 (jumonji and AT-rich interaction domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41035/jarid2-(jumonji-and-at-rich-interaction-domain-containing-2)