Identity
HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
KLKR,Klk6,hK1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3816
MIM: 147910
HGNC: 6357
Ensembl: ENSG00000167748
Variants:
dbSNP: 3816
ClinVar: 3816
TCGA: ENSG00000167748
COSMIC: KLK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167748 | ENST00000301420 | P06870 |
| ENSG00000167748 | ENST00000301420 | A0A1R3UCD2 |
| ENSG00000167748 | ENST00000593325 | M0R318 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33355364 | 2021 | Co‑expression of tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 improves myocardial ischemia‑reperfusion injury by promoting angiogenesis and inhibiting oxidative stress. | 2 |
| 33397811 | 2021 | Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. | 23 |
| 33355364 | 2021 | Co‑expression of tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 improves myocardial ischemia‑reperfusion injury by promoting angiogenesis and inhibiting oxidative stress. | 2 |
| 33397811 | 2021 | Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. | 23 |
| 30618416 | 2019 | Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia. | 7 |
| 30801944 | 2019 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. | 16 |
| 30908937 | 2019 | Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection. | 6 |
| 31873176 | 2019 | Associations of ACE I/D polymorphism with the levels of ACE, kallikrein, angiotensin II and interleukin-6 in STEMI patients. | 23 |
| 30618416 | 2019 | Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia. | 7 |
| 30801944 | 2019 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. | 16 |
| 30908937 | 2019 | Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection. | 6 |
| 31873176 | 2019 | Associations of ACE I/D polymorphism with the levels of ACE, kallikrein, angiotensin II and interleukin-6 in STEMI patients. | 23 |
| 28322037 | 2018 | Analysis of KLK1 polymorphism (rs5516) in patients with abdominal aortic aneurysm or thoracic aortic dissection. | 1 |
| 28322037 | 2018 | Analysis of KLK1 polymorphism (rs5516) in patients with abdominal aortic aneurysm or thoracic aortic dissection. | 1 |
| 28621557 | 2017 | A positive association between the human tissue kallikerin gene A2233C polymorphism and blood pressure response to benazepril. | 0 |
Citation
Dessen P
KLK1 (kallikrein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41075/klk1-(kallikrein-1)
