Identity
HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
KLK2A2,hGK-1,hK2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3817
MIM: 147960
HGNC: 6363
Ensembl: ENSG00000167751
Variants:
dbSNP: 3817
ClinVar: 3817
TCGA: ENSG00000167751
COSMIC: KLK2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38396898 | 2024 | Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2. | 0 |
| 38396898 | 2024 | Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2. | 0 |
| 34486998 | 2021 | Early prediction of prostate cancer biochemical recurrence and identification of disease persistence using PSA isoforms and human kallikrein-2. | 1 |
| 34486998 | 2021 | Early prediction of prostate cancer biochemical recurrence and identification of disease persistence using PSA isoforms and human kallikrein-2. | 1 |
| 32628300 | 2020 | Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer. | 9 |
| 32628300 | 2020 | Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer. | 9 |
| 31043681 | 2019 | Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer. | 2 |
| 31043681 | 2019 | Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer. | 2 |
| 26582203 | 2016 | A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity. | 9 |
| 26582203 | 2016 | A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity. | 9 |
| 25847286 | 2015 | Trp(250) -hK2 is defective in intracellular trafficking and activates the unfolded protein response. | 0 |
| 25847286 | 2015 | Trp(250) -hK2 is defective in intracellular trafficking and activates the unfolded protein response. | 0 |
| 24122203 | 2014 | Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation. | 23 |
| 24270797 | 2014 | Genetic variation in KLK2 and KLK3 is associated with concentrations of hK2 and PSA in serum and seminal plasma in young men. | 14 |
| 24711254 | 2014 | Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia. | 14 |
Citation
Dessen P
KLK2 (kallikrein related peptidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41082/klk2-(kallikrein-related-peptidase-2)
