KLRC3 (killer cell lectin like receptor C3)

2003-06-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
NKG2-E,NKG2E

Other Information

Locus ID:

NCBI: 3823
MIM: 602892
HGNC: 6376
Ensembl: ENSG00000205810

Variants:

dbSNP: 3823
ClinVar: 3823
TCGA: ENSG00000205810
COSMIC: KLRC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205810ENST00000381903Q07444
ENSG00000205810ENST00000396439Q07444

Expression (GTEx)

0
1
2
3
4
5

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
294674572018Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate.18
295458032018NKG2H-Expressing T Cells Negatively Regulate Immune Responses.6
294674572018Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate.18
295458032018NKG2H-Expressing T Cells Negatively Regulate Immune Responses.6
276410662017KLRC3, a Natural Killer receptor gene, is a key factor involved in glioblastoma tumourigenesis and aggressiveness.12
276410662017KLRC3, a Natural Killer receptor gene, is a key factor involved in glioblastoma tumourigenesis and aggressiveness.12
249359232014Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.16
249359232014Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.16
241771692013Low gene expression levels of activating receptors of natural killer cells (NKG2E and CD94) in patients with fulminant type 1 diabetes.8
241771692013Low gene expression levels of activating receptors of natural killer cells (NKG2E and CD94) in patients with fulminant type 1 diabetes.8

Citation

Dessen P

KLRC3 (killer cell lectin like receptor C3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41092/klrc3-(killer-cell-lectin-like-receptor-c3)