KRT19 (keratin 19)

2003-08-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
CK19,K19,K1CS
FUSION GENES

Other Information

Locus ID:

NCBI: 3880
MIM: 148020
HGNC: 6436
Ensembl: ENSG00000171345

Variants:

dbSNP: 3880
ClinVar: 3880
TCGA: ENSG00000171345
COSMIC: KRT19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171345ENST00000361566P08727
ENSG00000171345ENST00000455635C9JM50
ENSG00000171345ENST00000593096K7EMS3

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
166276852006The phenotypes of pluripotent human hepatic progenitors.101
220456742011Human hepatocellular carcinomas with "Stemness"-related marker expression: keratin 19 expression and a poor prognosis.93
168793912006The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin.88
239585572014Keratin 19: a key role player in the invasion of human hepatocellular carcinomas.76
254768972014A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma.68
184512212008Prognostic value of the molecular detection of circulating tumor cells using a multimarker reverse transcription-PCR assay for cytokeratin 19, mammaglobin A, and HER2 in early breast cancer.59
145566572003Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence.54
233520322013Diagnostic value of CEA and CYFRA 21-1 tumor markers in primary lung cancer.52
195493212009Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer.41
258204152015Keratin 19, a Cancer Stem Cell Marker in Human Hepatocellular Carcinoma.41

Citation

Dessen P

KRT19 (keratin 19)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41105/krt19-(keratin-19)