KTN1 (kinectin 1)

2003-02-01  

Identity

HGNC
KTN1
LOCATION
14q22.3
LOCUSID
3895
ALIAS
CG1,KNT,MU-RMS-40.19
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3895
MIM: 600381
HGNC: 6467
Ensembl: ENSG00000126777

Variants:

dbSNP: 3895
ClinVar: 3895
TCGA: ENSG00000126777
COSMIC: KTN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126777ENST00000395308Q86UP2
ENSG00000126777ENST00000395309Q86UP2
ENSG00000126777ENST00000395311Q86UP2
ENSG00000126777ENST00000395314Q86UP2
ENSG00000126777ENST00000395314A0A024R663
ENSG00000126777ENST00000413890Q86UP2
ENSG00000126777ENST00000438792Q86UP2
ENSG00000126777ENST00000459737Q86UP2
ENSG00000126777ENST00000459737A0A024R663
ENSG00000126777ENST00000553360H0YJZ8
ENSG00000126777ENST00000553624G3V5P0
ENSG00000126777ENST00000553710H0YJB7
ENSG00000126777ENST00000554294H0YJP2
ENSG00000126777ENST00000554507G3V4Y7
ENSG00000126777ENST00000554567G3V5Q0
ENSG00000126777ENST00000554570H0YJV5
ENSG00000126777ENST00000554890G3V5G2
ENSG00000126777ENST00000555498G3V4L8
ENSG00000126777ENST00000555573B7Z6P3
ENSG00000126777ENST00000557267G3V475

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases activate KTN1REACTOMER-HSA-5625970

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379925462024A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.0
384483402024KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage.0
379925462024A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.0
384483402024KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage.0
321158112021Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.5
342191292021Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity.5
345913542021Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.0
321158112021Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.5
342191292021Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity.5
345913542021Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.0
321909802020KTN1 variants and risk for attention deficit hyperactivity disorder.9
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9
329567412020Associations of attention distractibility with attention deficit and with variation in the KTN1 gene.2
321909802020KTN1 variants and risk for attention deficit hyperactivity disorder.9
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9

Citation

Dessen P

KTN1 (kinectin 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41108/deep-insight-explorer/favicon/welcome