LGALS3BP (galectin 3 binding protein)

2003-06-01   Dessen P  

Identity

HGNC
LGALS3BP
LOCATION
17q25.3
LOCUSID
3959
ALIAS
90K,BTBD17B,CyCAP,M2BP,MAC-2-BP,TANGO10B,gp90
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3959
MIM: 600626
HGNC: 6564
Ensembl: ENSG00000108679

Variants:

dbSNP: 3959
ClinVar: 3959
TCGA: ENSG00000108679
COSMIC: LGALS3BP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108679ENST00000262776Q08380
ENSG00000108679ENST00000262776A0A0S2Z3Y1
ENSG00000108679ENST00000585407K7EKQ5
ENSG00000108679ENST00000586720K7ELA1
ENSG00000108679ENST00000587251K7EN99
ENSG00000108679ENST00000587310K7ER67
ENSG00000108679ENST00000587311K7EQT9
ENSG00000108679ENST00000588198K7ERZ6
ENSG00000108679ENST00000588205K7EM15
ENSG00000108679ENST00000588899K7EM15
ENSG00000108679ENST00000588990K7ER67
ENSG00000108679ENST00000589527K7EP36
ENSG00000108679ENST00000589775K7ESM3
ENSG00000108679ENST00000589906K7EJY8
ENSG00000108679ENST00000591274K7ES75
ENSG00000108679ENST00000591778K7EJD3

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380380052024Diagnostic Value of Serum Galectin-3 Binding Protein Level in Patients with Pulmonary Arterial Hypertension.0
383218722024Potential of Mac-2-binding protein glycan isomer as a new therapeutic target in pancreatic cancer.1
383936922024LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma.0
380380052024Diagnostic Value of Serum Galectin-3 Binding Protein Level in Patients with Pulmonary Arterial Hypertension.0
383218722024Potential of Mac-2-binding protein glycan isomer as a new therapeutic target in pancreatic cancer.1
383936922024LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma.0
362452852023Platelet LGALS3BP as a Mediator of Myeloid Inflammation in Systemic Lupus Erythematosus.3
365087342023Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus.1
37162650202390K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.1
371860072023Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR-671-5p/LGALS3BP/NF-κB axis.2
371913532023Visualizing Galectin-3 Binding Protein Expression with ImmunoPET.0
374678912023Polymeric immunoglobulin receptor and galectin-3-binding protein are raised in biliary atresia: Reveals a proteomic-based study.2
362452852023Platelet LGALS3BP as a Mediator of Myeloid Inflammation in Systemic Lupus Erythematosus.3
365087342023Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus.1
37162650202390K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.1

Citation

Dessen P

LGALS3BP (galectin 3 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41143/lgals3bp-(galectin-3-binding-protein)