Identity
HGNC
LOCATION
14q32.12
LOCUSID
ALIAS
AEP,LGMN1,PRSC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5641
MIM: 602620
HGNC: 9472
Ensembl: ENSG00000100600
Variants:
dbSNP: 5641
ClinVar: 5641
TCGA: ENSG00000100600
COSMIC: LGMN
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36464174 | 2023 | Metformin regulates autophagy via LGMN to inhibit choriocarcinoma. | 2 |
| 36609651 | 2023 | Asparaginyl endopeptidase contributes to cetuximab resistance via MEK/ERK signaling in RAS wide-type metastatic colorectal cancer. | 0 |
| 37909538 | 2023 | Relationship between Increased Plasma Levels of Legumain and Properties of Coronary Atherosclerotic Plaque. | 1 |
| 37977223 | 2023 | c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6. | 0 |
| 37988165 | 2023 | AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments. | 3 |
| 38009231 | 2023 | Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease. | 0 |
| 36464174 | 2023 | Metformin regulates autophagy via LGMN to inhibit choriocarcinoma. | 2 |
| 36609651 | 2023 | Asparaginyl endopeptidase contributes to cetuximab resistance via MEK/ERK signaling in RAS wide-type metastatic colorectal cancer. | 0 |
| 37909538 | 2023 | Relationship between Increased Plasma Levels of Legumain and Properties of Coronary Atherosclerotic Plaque. | 1 |
| 37977223 | 2023 | c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6. | 0 |
| 37988165 | 2023 | AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments. | 3 |
| 38009231 | 2023 | Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease. | 0 |
| 35053409 | 2022 | Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene. | 3 |
| 35100526 | 2022 | Legumain Is an Endogenous Modulator of Integrin αvβ3 Triggering Vascular Degeneration, Dissection, and Rupture. | 37 |
| 35332331 | 2022 | An infection-induced oxidation site regulates legumain processing and tumor growth. | 6 |
Citation
Dessen P
LGMN (legumain)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41148/lgmn-(legumain)
