Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 89884
MIM: 602146
HGNC: 21734
Ensembl: ENSG00000121454
Variants:
dbSNP: 89884
ClinVar: 89884
TCGA: ENSG00000121454
COSMIC: LHX4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000121454 | ENST00000263726 | Q969G2 |
| ENSG00000121454 | ENST00000263726 | A0A0S2Z5S4 |
| ENSG00000121454 | ENST00000561113 | H0YKF4 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37948564 | 2023 | Genetic diagnosis of congenital hypopituitarism in Turkish patients by a target gene panel: novel pathogenic variants in GHRHR, GLI2, LHX4 and POU1F1 genes. | 0 |
| 37948564 | 2023 | Genetic diagnosis of congenital hypopituitarism in Turkish patients by a target gene panel: novel pathogenic variants in GHRHR, GLI2, LHX4 and POU1F1 genes. | 0 |
| 27820671 | 2017 | Contribution of LHX4 Mutations to Pituitary Deficits in a Cohort of 417 Unrelated Patients. | 9 |
| 27820671 | 2017 | Contribution of LHX4 Mutations to Pituitary Deficits in a Cohort of 417 Unrelated Patients. | 9 |
| 25871839 | 2015 | Novel Lethal Form of Congenital Hypopituitarism Associated With the First Recessive LHX4 Mutation. | 9 |
| 25955177 | 2015 | Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue. | 5 |
| 25871839 | 2015 | Novel Lethal Form of Congenital Hypopituitarism Associated With the First Recessive LHX4 Mutation. | 9 |
| 25955177 | 2015 | Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue. | 5 |
| 25034524 | 2014 | Oncogenicity of LHX4 in colorectal cancer through Wnt/β-catenin/TCF4 cascade. | 8 |
| 25034524 | 2014 | Oncogenicity of LHX4 in colorectal cancer through Wnt/β-catenin/TCF4 cascade. | 8 |
| 23199197 | 2013 | Pituitary stalk interruption syndrome in 58 Chinese patients: clinical features and genetic analysis. | 14 |
| 23199197 | 2013 | Pituitary stalk interruption syndrome in 58 Chinese patients: clinical features and genetic analysis. | 14 |
| 22232309 | 2012 | Panhypopituitarism presenting as life-threatening heart failure caused by an inherited microdeletion in 1q25 including LHX4. | 12 |
| 23029363 | 2012 | Gradual loss of ACTH due to a novel mutation in LHX4: comprehensive mutation screening in Japanese patients with congenital hypopituitarism. | 6 |
| 22232309 | 2012 | Panhypopituitarism presenting as life-threatening heart failure caused by an inherited microdeletion in 1q25 including LHX4. | 12 |
Citation
Dessen P
LHX4 (LIM homeobox 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41152/lhx4-(lim-homeobox-4)
