LITAF (lipopolysaccharide induced TNF factor)

2003-11-01  

Identity

HGNC
LITAF
LOCATION
16p13.13
LOCUSID
9516
ALIAS
PIG7,SIMPLE,TP53I7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9516
MIM: 603795
HGNC: 16841
Ensembl: ENSG00000189067

Variants:

dbSNP: 9516
ClinVar: 9516
TCGA: ENSG00000189067
COSMIC: LITAF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189067ENST00000339430Q99732
ENSG00000189067ENST00000381810Q99732
ENSG00000189067ENST00000413364Q99732
ENSG00000189067ENST00000570798I3L1I9
ENSG00000189067ENST00000570904Q99732
ENSG00000189067ENST00000571277I3L1R0
ENSG00000189067ENST00000571459I3L2E2
ENSG00000189067ENST00000571627I3L3U8
ENSG00000189067ENST00000571688Q99732
ENSG00000189067ENST00000571976I3L329
ENSG00000189067ENST00000572255I3L1H3
ENSG00000189067ENST00000573332I3L409
ENSG00000189067ENST00000574701I3L1P1
ENSG00000189067ENST00000574703I3L2T6
ENSG00000189067ENST00000574763Q99732
ENSG00000189067ENST00000574848I3L2T1
ENSG00000189067ENST00000575426A0A0G2JLC4
ENSG00000189067ENST00000576036Q99732
ENSG00000189067ENST00000576334I3L133
ENSG00000189067ENST00000620789Q99732
ENSG00000189067ENST00000622633Q99732

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382622612024Circ_0030042 inhibits trophoblast cell growth, invasion and epithelial-mesenchymal transition process in preeclampsia via miR-942-5p/LITAF.0
382622612024Circ_0030042 inhibits trophoblast cell growth, invasion and epithelial-mesenchymal transition process in preeclampsia via miR-942-5p/LITAF.0
356087742022Identification and clinical characterization of Charcot-Marie-Tooth disease type 1C patients with LITAF p.G112S mutation.1
356087742022Identification and clinical characterization of Charcot-Marie-Tooth disease type 1C patients with LITAF p.G112S mutation.1
343117272021Atypical presentation of Charcot-Marie-Tooth disease type 1C with a new mutation: a case report.0
343202382021SIMPLE Is an Endosomal Regulator That Protects Against NAFLD by Targeting the Lysosomal Degradation of EGFR.9
343117272021Atypical presentation of Charcot-Marie-Tooth disease type 1C with a new mutation: a case report.0
343202382021SIMPLE Is an Endosomal Regulator That Protects Against NAFLD by Targeting the Lysosomal Degradation of EGFR.9
331095622020Involvement of the MicroRNA-1-LITAF Axis in Gastric Cancer Cell Growth and Invasion.4
331095622020Involvement of the MicroRNA-1-LITAF Axis in Gastric Cancer Cell Growth and Invasion.4
305529892019A potential regulatory network among WDR86-AS1, miR-10b-3p, and LITAF is possibly involved in preeclampsia pathogenesis.8
310987712019LITAF Enhances Radiosensitivity of Human Glioma Cells via the FoxO1 Pathway.12
305529892019A potential regulatory network among WDR86-AS1, miR-10b-3p, and LITAF is possibly involved in preeclampsia pathogenesis.8
310987712019LITAF Enhances Radiosensitivity of Human Glioma Cells via the FoxO1 Pathway.12
298457142018miRNA-106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation.23

Citation

Dessen P

LITAF (lipopolysaccharide induced TNF factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41161/litaf-(lipopolysaccharide-induced-tnf-factor)