Identity
HGNC
LOCATION
4q24
LOCUSID
ALIAS
NHA2,NHE10,NHEDC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 133308
MIM: 611789
HGNC: 25143
Ensembl: ENSG00000164038
Variants:
dbSNP: 133308
ClinVar: 133308
TCGA: ENSG00000164038
COSMIC: SLC9B2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Stimuli-sensing channels | REACTOME | R-HSA-2672351 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36177733 | 2022 | Allosteric links between the hydrophilic N-terminus and transmembrane core of human Na(+) /H(+) antiporter NHA2. | 1 |
| 36177733 | 2022 | Allosteric links between the hydrophilic N-terminus and transmembrane core of human Na(+) /H(+) antiporter NHA2. | 1 |
| 28154142 | 2017 | Dissecting the proton transport pathway in electrogenic Na(+)/H(+) antiporters. | 27 |
| 28154142 | 2017 | Dissecting the proton transport pathway in electrogenic Na(+)/H(+) antiporters. | 27 |
| 22948142 | 2012 | Unconventional chemiosmotic coupling of NHA2, a mammalian Na+/H+ antiporter, to a plasma membrane H+ gradient. | 20 |
| 22948142 | 2012 | Unconventional chemiosmotic coupling of NHA2, a mammalian Na+/H+ antiporter, to a plasma membrane H+ gradient. | 20 |
| 20053353 | 2010 | Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension. | 22 |
| 20332099 | 2010 | A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. | 8 |
| 20713131 | 2010 | Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae. | 3 |
| 20053353 | 2010 | Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension. | 22 |
| 20332099 | 2010 | A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. | 8 |
| 20713131 | 2010 | Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae. | 3 |
| 17988971 | 2008 | NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts. | 21 |
| 18508966 | 2008 | Characterization of the sodium/hydrogen exchanger NHA2. | 28 |
| 17988971 | 2008 | NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts. | 21 |
Citation
Dessen P
SLC9B2 (solute carrier family 9 member B2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41169/slc9b2-(solute-carrier-family-9-member-b2)
