INTS12 (integrator complex subunit 12)

2003-05-01  

Identity

HGNC
INTS12
LOCATION
4q24
LOCUSID
57117
ALIAS
INT12,PHF22,SBBI22
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57117
MIM: 611355
HGNC: 25067
Ensembl: ENSG00000138785

Variants:

dbSNP: 57117
ClinVar: 57117
TCGA: ENSG00000138785
COSMIC: INTS12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138785ENST00000340139Q96CB8
ENSG00000138785ENST00000340139A0A024RDK4
ENSG00000138785ENST00000394735Q96CB8
ENSG00000138785ENST00000394735A0A024RDK4
ENSG00000138785ENST00000416543C9JDP3
ENSG00000138785ENST00000420368C9J0M6
ENSG00000138785ENST00000433009A0A1B0GX90
ENSG00000138785ENST00000451321Q96CB8
ENSG00000138785ENST00000451321A0A024RDK4
ENSG00000138785ENST00000503746E9PGI3
ENSG00000138785ENST00000510876D6R9W3
ENSG00000138785ENST00000515819D6R9Y5
ENSG00000138785ENST00000618810A0A087WXN4

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
283357322017Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways.10
283357322017Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways.10
240586082013GSTCD and INTS12 regulation and expression in the human lung.27
240586082013GSTCD and INTS12 regulation and expression in the human lung.27
200108352010Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.309
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8
200108352010Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.309
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8

Citation

Dessen P

INTS12 (integrator complex subunit 12)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41181/ints12-(integrator-complex-subunit-12)