LRRC14 (leucine rich repeat containing 14)

2003-05-01 Affiliation

Identity

HGNC

LRRC14

LOCATION

8q24.3

LOCUSID

9684

ALIAS

LRRC14A

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9684
HGNC: 20419
Ensembl: ENSG00000160959

Variants:

dbSNP: 9684
ClinVar: 9684
TCGA: ENSG00000160959
COSMIC: LRRC14

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000160959	ENST00000292524	Q15048
ENSG00000160959	ENST00000525766	E9PNL0
ENSG00000160959	ENST00000527730	E9PP40
ENSG00000160959	ENST00000529022	Q15048
ENSG00000160959	ENST00000530854	E9PRP5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
27426725	2016	LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex.	4
27426725	2016	LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex.	4

Citation

Dessen P

LRRC14 (leucine rich repeat containing 14)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41201/lrrc14-(leucine-rich-repeat-containing-14)