Identity
HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
C14orf141,GLC3D,LTBP3,MSPKA,MSTP031,WMS3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4053
MIM: 602091
HGNC: 6715
Ensembl: ENSG00000119681
Variants:
dbSNP: 4053
ClinVar: 4053
TCGA: ENSG00000119681
COSMIC: LTBP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119681 | ENST00000261978 | Q14767 |
| ENSG00000119681 | ENST00000553939 | G3V511 |
| ENSG00000119681 | ENST00000556206 | H0YJ20 |
| ENSG00000119681 | ENST00000556690 | G3V3X5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| Elastic fibre formation | REACTOME | R-HSA-1566948 |
| Molecules associated with elastic fibres | REACTOME | R-HSA-2129379 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38772353 | 2024 | Autosomal Dominant Weill-Marchesani-Like Syndrome in a Chinese Family due to Novel Haplotypic Mutations in LTBP2. | 0 |
| 38772353 | 2024 | Autosomal Dominant Weill-Marchesani-Like Syndrome in a Chinese Family due to Novel Haplotypic Mutations in LTBP2. | 0 |
| 37864077 | 2023 | Plasma LTBP2 as a potential biomarker in differential diagnosis of connective tissue disease-associated interstitial lung disease and idiopathic pulmonary fibrosis: a pilot study. | 0 |
| 38222456 | 2023 | Identification and phenotypic analysis of novel LTBP2 mutations in a Chinese cohort with congenital ectopia lentis. | 0 |
| 37864077 | 2023 | Plasma LTBP2 as a potential biomarker in differential diagnosis of connective tissue disease-associated interstitial lung disease and idiopathic pulmonary fibrosis: a pilot study. | 0 |
| 38222456 | 2023 | Identification and phenotypic analysis of novel LTBP2 mutations in a Chinese cohort with congenital ectopia lentis. | 0 |
| 35235125 | 2022 | CircWHSC1 expedites cervical cancer progression via miR-532-3p/LTBP2 axis. | 2 |
| 35512078 | 2022 | The prognostic significance of LTBP2 for malignant tumors: Evidence based on 11 observational studies. | 1 |
| 35968244 | 2022 | LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62-Keap1-Nrf2 Pathway. | 3 |
| 35235125 | 2022 | CircWHSC1 expedites cervical cancer progression via miR-532-3p/LTBP2 axis. | 2 |
| 35512078 | 2022 | The prognostic significance of LTBP2 for malignant tumors: Evidence based on 11 observational studies. | 1 |
| 35968244 | 2022 | LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62-Keap1-Nrf2 Pathway. | 3 |
| 34481123 | 2021 | Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2. | 5 |
| 34481123 | 2021 | Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2. | 5 |
| 32165823 | 2020 | Novel mutations in LTBP2 identified in familial cases of primary congenital glaucoma. | 10 |
Citation
Dessen P
LTBP2 (latent transforming growth factor beta binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/41213/ltbp2-(latent-transforming-growth-factor-beta-binding-protein-2)
