Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4058
MIM: 151520
HGNC: 6721
Ensembl: ENSG00000062524
Variants:
dbSNP: 4058
ClinVar: 4058
TCGA: ENSG00000062524
COSMIC: LTK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000062524 | ENST00000263800 | P29376 |
| ENSG00000062524 | ENST00000355166 | P29376 |
| ENSG00000062524 | ENST00000453182 | P29376 |
| ENSG00000062524 | ENST00000561619 | H3BVG6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38517106 | 2024 | Spindle cell neoplasms with novel LTK fusion - Expanding the spectrum of kinase fusion-positive soft tissue tumors. | 0 |
| 38517106 | 2024 | Spindle cell neoplasms with novel LTK fusion - Expanding the spectrum of kinase fusion-positive soft tissue tumors. | 0 |
| 34646012 | 2021 | Structural basis of cytokine-mediated activation of ALK family receptors. | 17 |
| 34819663 | 2021 | The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer. | 29 |
| 34646012 | 2021 | Structural basis of cytokine-mediated activation of ALK family receptors. | 17 |
| 34819663 | 2021 | The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer. | 29 |
| 31227593 | 2019 | LTK is an ER-resident receptor tyrosine kinase that regulates secretion. | 22 |
| 31227593 | 2019 | LTK is an ER-resident receptor tyrosine kinase that regulates secretion. | 22 |
| 26630010 | 2015 | Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions. | 0 |
| 26630010 | 2015 | Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions. | 0 |
| 25331893 | 2014 | Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome. | 30 |
| 25331893 | 2014 | Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome. | 30 |
| 22347506 | 2012 | ALK-activating homologous mutations in LTK induce cellular transformation. | 19 |
| 22347506 | 2012 | ALK-activating homologous mutations in LTK induce cellular transformation. | 19 |
| 14695357 | 2004 | Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. | 14 |
Citation
Dessen P
LTK (leukocyte receptor tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41218/ltk-(leukocyte-receptor-tyrosine-kinase)
