MAFF (MAF bZIP transcription factor F)

2003-12-01  

Identity

HGNC
MAFF
LOCATION
22q13.1
LOCUSID
23764
ALIAS
U-MAF,hMafF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23764
MIM: 604877
HGNC: 6780
Ensembl: ENSG00000185022

Variants:

dbSNP: 23764
ClinVar: 23764
TCGA: ENSG00000185022
COSMIC: MAFF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185022ENST00000338483Q9ULX9
ENSG00000185022ENST00000407965Q9ULX9
ENSG00000185022ENST00000417948B0QY70
ENSG00000185022ENST00000426621Q9ULX9
ENSG00000185022ENST00000441709B0QY71
ENSG00000185022ENST00000538320Q9ULX9
ENSG00000185022ENST00000538999Q9ULX9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA283MAPK8GenePathwayassociated23922006
PA30621MAPK14GenePathwayassociated23922006

References

Pubmed IDYearTitleCitations
336268822021Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.19
339805952021MafF Is an Antiviral Host Factor That Suppresses Transcription from Hepatitis B Virus Core Promoter.8
342620282021The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.32
336268822021Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.19
339805952021MafF Is an Antiviral Host Factor That Suppresses Transcription from Hepatitis B Virus Core Promoter.8
342620282021The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.32
323393542020Alternative splicing related genetic variants contribute to bladder cancer risk.19
334888462020Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.10
323393542020Alternative splicing related genetic variants contribute to bladder cancer risk.19
334888462020Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress.10
306691882019Regulation of CXCL1 chemokine and CSF3 cytokine levels in myometrial cells by the MAFF transcription factor.10
306691882019Regulation of CXCL1 chemokine and CSF3 cytokine levels in myometrial cells by the MAFF transcription factor.10
297572602018Involvement of MAFB and MAFF in Retinoid-Mediated Suppression of Hepatocellular Carcinoma Invasion.8
297572602018Involvement of MAFB and MAFF in Retinoid-Mediated Suppression of Hepatocellular Carcinoma Invasion.8
241184572014Small MAF genes variants and chronic myeloid leukemia.10

Citation

Dessen P

MAFF (MAF bZIP transcription factor F)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41237/maff-(maf-bzip-transcription-factor-f)