MALAT1 (metastasis associated lung adenocarcinoma transcript 1)

2003-10-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
HCN,LINC00047,NCRNA00047,NEAT2,PRO2853
FUSION GENES

Other Information

Locus ID:

NCBI: 378938
MIM: 607924
HGNC: 29665
Ensembl: ENSG00000251562

Variants:

dbSNP: 378938
ClinVar: 378938
TCGA: ENSG00000251562
COSMIC: MALAT1

RNA/Proteins

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713176Platinum compoundsChemicalClinicalAnnotationassociatedPD26729200
PA444818Lung NeoplasmsDiseaseClinicalAnnotationassociatedPD26729200

References

Pubmed IDYearTitleCitations
235552852013Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB.261
220788782011ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs.251
256006452015Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205.208
244498232014TGF-β-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12.167
250259662014Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex.142
254312572015MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway.110
257872492015Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells.102
254469872015MALAT1 promotes colorectal cancer cell proliferation/migration/invasion via PRKA kinase anchor protein 9.83
264612242015LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma.71
280698782017MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2.70

Citation

Dessen P

MALAT1 (metastasis associated lung adenocarcinoma transcript 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/41266/malat1-(metastasis-associated-lung-adenocarcinoma-transcript-1)