MAP3K9 (mitogen-activated protein kinase kinase kinase 9)

2003-02-01  

Identity

HGNC
LOCATION
14q24.2
LOCUSID
ALIAS
MEKK9,MLK1,PRKE1
FUSION GENES

Other Information

Locus ID:

NCBI: 4293
MIM: 600136
HGNC: 6861
Ensembl: ENSG00000006432

Variants:

dbSNP: 4293
ClinVar: 4293
TCGA: ENSG00000006432
COSMIC: MAP3K9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006432ENST00000381250J3KPI6
ENSG00000006432ENST00000553414G3V347
ENSG00000006432ENST00000554146G3V4P9
ENSG00000006432ENST00000554752P80192
ENSG00000006432ENST00000555993P80192
ENSG00000006432ENST00000611979A0A087WW79

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
MAPK (JNK) signalingKEGGhsa_M00688
MAPK (p38) signalingKEGGhsa_M00689
MAPK (JNK) signalingKEGGM00688
MAPK (p38) signalingKEGGM00689

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
221979302011Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.83
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
238366712013Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.21
282986432017MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response.13
280814682017Role of miR-15a in intervertebral disc degeneration through targeting MAP3K9.6
265730182016MicroRNA-148b enhances proliferation and apoptosis in human renal cancer cells via directly targeting MAP3K9.5
198260022009Repression of the estrogen receptor-alpha transcriptional activity by the Rho/megakaryoblastic leukemia 1 signaling pathway.4
311154912019miR‑490‑5p regulates the proliferation, migration, invasion and epithelial‑mesenchymal transition of pharyngolaryngeal cancer cells by targeting mitogen‑activated protein kinase kinasekinase 9.1

Citation

Dessen P

MAP3K9 (mitogen-activated protein kinase kinase kinase 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41285/map3k9-(mitogen-activated-protein-kinase-kinase-kinase-9)