MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)

2003-02-01  

Identity

HGNC
MAS1
LOCATION
6q25.3
LOCUSID
4142
ALIAS
MAS,MGRA

Other Information

Locus ID:

NCBI: 4142
MIM: 165180
HGNC: 6899
Ensembl: ENSG00000130368

Variants:

dbSNP: 4142
ClinVar: 4142
TCGA: ENSG00000130368
COSMIC: MAS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130368ENST00000252660P04201
ENSG00000130368ENST00000252660W8W3P4
ENSG00000130368ENST00000674077W8W3P4

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Renin-angiotensin systemKEGGko04614
Neuroactive ligand-receptor interactionKEGGhsa04080
Renin-angiotensin systemKEGGhsa04614

References

Pubmed IDYearTitleCitations
380614172024Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy.3
383507252024Myeloid-Mas Signaling Modulates Pathogenic Crosstalk among MYC(+)CD63(+) Endothelial Cells, MMP12(+) Macrophages, and Monocytes in Acetaminophen-Induced Liver Injury.3
380614172024Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy.3
383507252024Myeloid-Mas Signaling Modulates Pathogenic Crosstalk among MYC(+)CD63(+) Endothelial Cells, MMP12(+) Macrophages, and Monocytes in Acetaminophen-Induced Liver Injury.3
366312002023Mas receptor endocytosis and signaling in health and disease.0
366312002023Mas receptor endocytosis and signaling in health and disease.0
353285062022Neuroinflammation and COVID-19 Ischemic Stroke Recovery-Evolving Evidence for the Mediating Roles of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis and NLRP3 Inflammasome.9
353633332022The function of the ACE2/Ang(1-7)/Mas receptor axis of the renin-angiotensin system in myocardial ischemia reperfusion injury.4
361484742022Sex Difference in MasR Expression and Functions in the Renal System.1
353285062022Neuroinflammation and COVID-19 Ischemic Stroke Recovery-Evolving Evidence for the Mediating Roles of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis and NLRP3 Inflammasome.9
353633332022The function of the ACE2/Ang(1-7)/Mas receptor axis of the renin-angiotensin system in myocardial ischemia reperfusion injury.4
361484742022Sex Difference in MasR Expression and Functions in the Renal System.1
327641182021Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation.20
335119922021ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease.22
341248082021Human placenta mesenchymal stem cell protection in ischemic stroke is angiotensin converting enzyme-2 and masR receptor-dependent.14

Citation

Dessen P

MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41302/mas1-(mas1-proto-oncogene-g-protein-coupled-receptor)