Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9656
MIM: 607593
HGNC: 21163
Ensembl: ENSG00000137337
Variants:
dbSNP: 9656
ClinVar: 9656
TCGA: ENSG00000137337
COSMIC: MDC1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37962983 | 2024 | Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease. | 1 |
| 37962983 | 2024 | Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease. | 1 |
| 36640322 | 2023 | MDC1 maintains active elongation complexes of RNA polymerase II. | 0 |
| 37170184 | 2023 | A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer. | 0 |
| 36640322 | 2023 | MDC1 maintains active elongation complexes of RNA polymerase II. | 0 |
| 37170184 | 2023 | A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer. | 0 |
| 34877804 | 2022 | Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci. | 2 |
| 35378404 | 2022 | Functional defects of cancer-associated MDC1 mutations in DNA damage repair. | 3 |
| 36175703 | 2022 | Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair. | 1 |
| 34877804 | 2022 | Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci. | 2 |
| 35378404 | 2022 | Functional defects of cancer-associated MDC1 mutations in DNA damage repair. | 3 |
| 36175703 | 2022 | Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair. | 1 |
| 33947745 | 2021 | Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast. | 6 |
| 34321534 | 2021 | Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study. | 4 |
| 33947745 | 2021 | Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast. | 6 |
Citation
Dessen P
MDC1 (mediator of DNA damage checkpoint 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41326/mdc1-(mediator-of-dna-damage-checkpoint-1)
