RAB7B (RAB7B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
RAB7B
LOCATION
1q32.1
LOCUSID
338382
ALIAS
RAB7

Other Information

Locus ID:

NCBI: 338382
HGNC: 30513
Ensembl: ENSG00000276600

Variants:

dbSNP: 338382
ClinVar: 338382
TCGA: ENSG00000276600
COSMIC: RAB7B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276600ENST00000617070Q96AH8
ENSG00000276600ENST00000617991Q96AH8
ENSG00000276600ENST00000622969A0A096LPF0
ENSG00000276600ENST00000623597Q96AH8
ENSG00000276600ENST00000623893A0A096LP44

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
AmoebiasisKEGGko05146
AmoebiasisKEGGhsa05146
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137

References

Pubmed IDYearTitleCitations
366560162023Listeria InlB Expedites Vacuole Escape and Intracellular Proliferation by Promoting Rab7 Recruitment via Vps34.1
366560162023Listeria InlB Expedites Vacuole Escape and Intracellular Proliferation by Promoting Rab7 Recruitment via Vps34.1
344940972021Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton.10
344940972021Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton.10
311530542019Rab7b participation on the TLR4 (Toll-like receptor) endocytic pathway in Shiga toxin-associated Hemolytic Uremic Syndrome (HUS).3
311530542019Rab7b participation on the TLR4 (Toll-like receptor) endocytic pathway in Shiga toxin-associated Hemolytic Uremic Syndrome (HUS).3
301115802018TBC1D5 controls the GTPase cycle of Rab7b.24
301115802018TBC1D5 controls the GTPase cycle of Rab7b.24
288355452017Rab7b modulates autophagic flux by interacting with Atg4B.22
288355452017Rab7b modulates autophagic flux by interacting with Atg4B.22
259965262015Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells.22
259965262015Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells.22
233455142013Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection.97
233455142013Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection.97
227087382012Dynamics of Rab7b-dependent transport of sorting receptors.23

Citation

Dessen P

RAB7B (RAB7B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41357/rab7b-(rab7b-member-ras-oncogene-family)