Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2872
MIM: 605069
HGNC: 7111
Ensembl: ENSG00000099875
Variants:
dbSNP: 2872
ClinVar: 2872
TCGA: ENSG00000099875
COSMIC: MKNK2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36764601 | 2023 | MNK1 and MNK2 Expression in the Human Dorsal Root and Trigeminal Ganglion. | 3 |
| 36764601 | 2023 | MNK1 and MNK2 Expression in the Human Dorsal Root and Trigeminal Ganglion. | 3 |
| 32170339 | 2021 | Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis. | 9 |
| 33564073 | 2021 | MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. | 8 |
| 33602301 | 2021 | SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma. | 31 |
| 33836345 | 2021 | MKNK2 enhances chemoresistance of ovarian cancer by suppressing autophagy via miR-125b. | 6 |
| 32170339 | 2021 | Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis. | 9 |
| 33564073 | 2021 | MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. | 8 |
| 33602301 | 2021 | SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma. | 31 |
| 33836345 | 2021 | MKNK2 enhances chemoresistance of ovarian cancer by suppressing autophagy via miR-125b. | 6 |
| 30329087 | 2018 | Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment. | 33 |
| 30329087 | 2018 | Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment. | 33 |
| 28878291 | 2017 | MAP kinase-interacting serine/threonine kinase 2 promotes proliferation, metastasis, and predicts poor prognosis in non-small cell lung cancer. | 14 |
| 28878291 | 2017 | MAP kinase-interacting serine/threonine kinase 2 promotes proliferation, metastasis, and predicts poor prognosis in non-small cell lung cancer. | 14 |
| 26668315 | 2016 | Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin. | 16 |
Citation
Dessen P
MKNK2 (MAPK interacting serine/threonine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41372/mknk2-(mapk-interacting-serine-threonine-kinase-2)
