MLF2 (myeloid leukemia factor 2)

2003-02-01  

Identity

HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
NTN4
FUSION GENES

Other Information

Locus ID:

NCBI: 8079
MIM: 601401
HGNC: 7126
Ensembl: ENSG00000089693

Variants:

dbSNP: 8079
ClinVar: 8079
TCGA: ENSG00000089693
COSMIC: MLF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089693ENST00000203630Q15773
ENSG00000089693ENST00000203630Q5U0N1
ENSG00000089693ENST00000435120Q15773
ENSG00000089693ENST00000435120Q5U0N1
ENSG00000089693ENST00000536207F5H7L5
ENSG00000089693ENST00000537126F5H0Y3
ENSG00000089693ENST00000539187Q15773
ENSG00000089693ENST00000539187Q5U0N1
ENSG00000089693ENST00000540710F5H800
ENSG00000089693ENST00000542154Q15773
ENSG00000089693ENST00000542154Q5U0N1

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
318318542020The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis.4
323421072020Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2.28
327034002020CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs).4
318318542020The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis.4
323421072020Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2.28
327034002020CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs).4
278401552017Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.8
278401552017Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.8
248762732014Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling.64
248762732014Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling.64
180951542008Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.10
180951542008Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.10

Citation

Dessen P

MLF2 (myeloid leukemia factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41374/mlf2-(myeloid-leukemia-factor-2)