MNT (MAX network transcriptional repressor)

2003-02-01  

Identity

HGNC
MNT
LOCATION
17p13.3
LOCUSID
4335
ALIAS
MAD6,MXD6,ROX,bHLHd3,lncRNA-HAL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4335
MIM: 603039
HGNC: 7188
Ensembl: ENSG00000070444

Variants:

dbSNP: 4335
ClinVar: 4335
TCGA: ENSG00000070444
COSMIC: MNT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000070444ENST00000174618Q99583
ENSG00000070444ENST00000575394V9GY02

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
344603312021Mnt Represses Epithelial Identity To Promote Epithelial-to-Mesenchymal Transition.3
344603312021Mnt Represses Epithelial Identity To Promote Epithelial-to-Mesenchymal Transition.3
319190962020The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells.8
319190962020The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells.8
270189482016DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation.18
270189482016DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation.18
247318542015The activities of MYC, MNT and the MAX-interactome in lymphocyte proliferation and oncogenesis.20
247318542015The activities of MYC, MNT and the MAX-interactome in lymphocyte proliferation and oncogenesis.20
238604462013Chromatin dynamics at the hTERT promoter during transcriptional activation and repression by c-Myc and Mnt in Xenopus leavis oocytes.3
238604462013Chromatin dynamics at the hTERT promoter during transcriptional activation and repression by c-Myc and Mnt in Xenopus leavis oocytes.3
229643332012Identification of Max binding protein as a novel binding protein of Nck1 and characterization of its role in inhibiting human liver cancer SK-HEP-1 cells.1
229643332012Identification of Max binding protein as a novel binding protein of Nck1 and characterization of its role in inhibiting human liver cancer SK-HEP-1 cells.1
190860362009Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.33
190860362009Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.33
181557222008Elucidation of the structural determinants responsible for the specific formation of heterodimeric Mxd1/Max b-HLH-LZ and its binding to E-box sequences.2

Citation

Dessen P

MNT (MAX network transcriptional repressor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41412/mnt-(max-network-transcriptional-repressor)