MPP1 (membrane palmitoylated protein 1)

2003-06-01  

Identity

HGNC
MPP1
LOCATION
Xq28
LOCUSID
4354
ALIAS
AAG12,DXS552E,EMP55,MRG1,PEMP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4354
MIM: 305360
HGNC: 7219
Ensembl: ENSG00000130830

Variants:

dbSNP: 4354
ClinVar: 4354
TCGA: ENSG00000130830
COSMIC: MPP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130830ENST00000369531A6NFY0
ENSG00000130830ENST00000369534Q00013
ENSG00000130830ENST00000393529A8MTH1
ENSG00000130830ENST00000393531Q00013
ENSG00000130830ENST00000413259Q00013
ENSG00000130830ENST00000417435F8WDV6
ENSG00000130830ENST00000428488C9JB34
ENSG00000130830ENST00000439370F8WC84
ENSG00000130830ENST00000453245C9J9J4

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
retina
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
286536542017MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer.0
288657982017MPP1 directly interacts with flotillins in erythrocyte membrane - Possible mechanism of raft domain formation.15
291469102017An unexpected protein interaction promotes drug resistance in leukemia.14
286536542017MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer.0
288657982017MPP1 directly interacts with flotillins in erythrocyte membrane - Possible mechanism of raft domain formation.15
291469102017An unexpected protein interaction promotes drug resistance in leukemia.14
254083372015Membrane rafts in the erythrocyte membrane: a novel role of MPP1p55.4
254083372015Membrane rafts in the erythrocyte membrane: a novel role of MPP1p55.4
235071982013The role of MPP1/p55 and its palmitoylation in resting state raft organization in HEL cells.13
235071982013The role of MPP1/p55 and its palmitoylation in resting state raft organization in HEL cells.13
215095942011Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.7
215095942011Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.7
189521292009Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells.9
191448712009Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.9
189521292009Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells.9

Citation

Dessen P

MPP1 (membrane palmitoylated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41420/mpp1-(membrane-palmitoylated-protein-1)