Identity
HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
IRAG,JAW1L,MRVI1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10335
MIM: 604673
HGNC: 7237
Ensembl: ENSG00000072952
Variants:
dbSNP: 10335
ClinVar: 10335
TCGA: ENSG00000072952
COSMIC: IRAG1
RNA/Proteins
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32573102 | 2020 | Homozygous mutation in murine retrovirus integration site 1 gene associated with a non-syndromic form of isolated familial achalasia. | 2 |
| 32589066 | 2020 | P53-induced MRVI1 mediates carcinogenesis of colorectal cancer. | 3 |
| 32573102 | 2020 | Homozygous mutation in murine retrovirus integration site 1 gene associated with a non-syndromic form of isolated familial achalasia. | 2 |
| 32589066 | 2020 | P53-induced MRVI1 mediates carcinogenesis of colorectal cancer. | 3 |
| 31085718 | 2019 | miR-940 potentially promotes proliferation and metastasis of endometrial carcinoma through regulation of MRVI1. | 20 |
| 31085718 | 2019 | miR-940 potentially promotes proliferation and metastasis of endometrial carcinoma through regulation of MRVI1. | 20 |
| 30001348 | 2018 | Whole exome sequencing identifies MRVI1 as a susceptibility gene for moyamoya syndrome in neurofibromatosis type 1. | 14 |
| 30001348 | 2018 | Whole exome sequencing identifies MRVI1 as a susceptibility gene for moyamoya syndrome in neurofibromatosis type 1. | 14 |
| 21865585 | 2011 | Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction. | 3 |
| 21865585 | 2011 | Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction. | 3 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20526338 | 2010 | Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. | 122 |
| 20567233 | 2010 | Functional osteoclast attachment requires inositol-1,4,5-trisphosphate receptor-associated cGMP-dependent kinase substrate. | 9 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
Citation
Dessen P
IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41431/irag1-(inositol-1-4-5-triphosphate-receptor-associated-1)
