MSR1 (macrophage scavenger receptor 1)

2003-02-01  

Identity

HGNC
MSR1
LOCATION
8p22
LOCUSID
4481
ALIAS
CD204,SCARA1,SR-A,SR-AI,SR-AII,SR-AIII,SRA,phSR1,phSR2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4481
MIM: 153622
HGNC: 7376
Ensembl: ENSG00000038945

Variants:

dbSNP: 4481
ClinVar: 4481
TCGA: ENSG00000038945
COSMIC: MSR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000038945ENST00000262101P21757
ENSG00000038945ENST00000350896P21757
ENSG00000038945ENST00000355282P21757
ENSG00000038945ENST00000381998P21757
ENSG00000038945ENST00000445506B4DDJ5
ENSG00000038945ENST00000518026E5RI91
ENSG00000038945ENST00000518960E5RFW8
ENSG00000038945ENST00000519060E5RFI4
ENSG00000038945ENST00000522672H0YBY2

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging by Class A ReceptorsREACTOMER-HSA-3000480

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365150672023Comprehensive analysis of immune cell infiltration and role of MSR1 expression in aneurysmal subarachnoid haemorrhage.3
368490722023Scavenger receptor a mediates glycated LDL transcytosis across endothelial cells to promote atherosclerosis.0
375803952023Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen.4
376321922023Role of macrophage scavenger receptor 1 in the progression of dyslipidemia in acne vulgaris patients.5
365150672023Comprehensive analysis of immune cell infiltration and role of MSR1 expression in aneurysmal subarachnoid haemorrhage.3
368490722023Scavenger receptor a mediates glycated LDL transcytosis across endothelial cells to promote atherosclerosis.0
375803952023Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen.4
376321922023Role of macrophage scavenger receptor 1 in the progression of dyslipidemia in acne vulgaris patients.5
350349072022MSR1 and NEP Are Correlated with Alzheimer's Disease Amyloid Pathology and Apolipoprotein Alterations.3
351421092022Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.9
360959482022MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression.9
365912282022Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis.0
350349072022MSR1 and NEP Are Correlated with Alzheimer's Disease Amyloid Pathology and Apolipoprotein Alterations.3
351421092022Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.9
360959482022MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression.9

Citation

Dessen P

MSR1 (macrophage scavenger receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41435/msr1-(macrophage-scavenger-receptor-1)