MYCBP (MYC binding protein)

2003-02-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
AMY-1
FUSION GENES

Other Information

Locus ID:

NCBI: 26292
MIM: 606535
HGNC: 7554
Ensembl: ENSG00000214114

Variants:

dbSNP: 26292
ClinVar: 26292
TCGA: ENSG00000214114
COSMIC: MYCBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214114ENST00000397572Q99417
ENSG00000214114ENST00000494695A0A0D9SEI7

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
205629182010Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein.58
175950612007c-myc promoter binding protein regulates the cellular response to an altered glucose concentration.18
168668772006AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.14
124148072002AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.11
122234832002AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase.10
205443962010PinX1 inhibits telomerase activity in gastric cancer cells through Mad1/c-Myc pathway.8
114836022001AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase.7
310940232019Non-coding RNA MFI2-AS1 promotes colorectal cancer cell proliferation, migration and invasion through miR-574-5p/MYCBP axis.7
220505662011Downregulation of c-Myc in pterygium and cultured pterygial cells.3

Citation

Dessen P

MYCBP (MYC binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41470/mycbp-(myc-binding-protein)