Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
NMMHC-IIB,NMMHCB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4628
MIM: 160776
HGNC: 7568
Ensembl: ENSG00000133026
Variants:
dbSNP: 4628
ClinVar: 4628
TCGA: ENSG00000133026
COSMIC: MYH10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000133026 | ENST00000269243 | P35580 |
| ENSG00000133026 | ENST00000360416 | P35580 |
| ENSG00000133026 | ENST00000379980 | P35580 |
| ENSG00000133026 | ENST00000411957 | E7ERA5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38019611 | 2024 | Mechanisms underlying Myosin 10's contribution to the maintenance of mitotic spindle bipolarity. | 0 |
| 38517106 | 2024 | Spindle cell neoplasms with novel LTK fusion - Expanding the spectrum of kinase fusion-positive soft tissue tumors. | 0 |
| 38019611 | 2024 | Mechanisms underlying Myosin 10's contribution to the maintenance of mitotic spindle bipolarity. | 0 |
| 38517106 | 2024 | Spindle cell neoplasms with novel LTK fusion - Expanding the spectrum of kinase fusion-positive soft tissue tumors. | 0 |
| 36929633 | 2023 | MYH10 Combines with MYH9 to Recruit USP45 by Deubiquitinating Snail and Promotes Serous Ovarian Cancer Carcinogenesis, Progression, and Cisplatin Resistance. | 5 |
| 36929633 | 2023 | MYH10 Combines with MYH9 to Recruit USP45 by Deubiquitinating Snail and Promotes Serous Ovarian Cancer Carcinogenesis, Progression, and Cisplatin Resistance. | 5 |
| 35980381 | 2022 | Heterozygous variants in MYH10 associated with neurodevelopmental disorders and congenital anomalies with evidence for primary cilia-dependent defects in Hedgehog signaling. | 3 |
| 35980381 | 2022 | Heterozygous variants in MYH10 associated with neurodevelopmental disorders and congenital anomalies with evidence for primary cilia-dependent defects in Hedgehog signaling. | 3 |
| 33415745 | 2021 | The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells. | 9 |
| 34060193 | 2021 | GATA1 pathogenic variants disrupt MYH10 silencing during megakaryopoiesis. | 3 |
| 34738311 | 2021 | Down-regulation of MYH10 driven by chromosome 17p13.1 deletion promotes hepatocellular carcinoma metastasis through activation of the EGFR pathway. | 8 |
| 33415745 | 2021 | The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells. | 9 |
| 34060193 | 2021 | GATA1 pathogenic variants disrupt MYH10 silencing during megakaryopoiesis. | 3 |
| 34738311 | 2021 | Down-regulation of MYH10 driven by chromosome 17p13.1 deletion promotes hepatocellular carcinoma metastasis through activation of the EGFR pathway. | 8 |
| 31489966 | 2020 | Network-based analysis reveals novel gene signatures in the peripheral blood of patients with sporadic nonsyndromic thoracic aortic aneurysm. | 5 |
Citation
Dessen P
MYH10 (myosin heavy chain 10)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41478/myh10-(myosin-heavy-chain-10)
