Identity
HGNC
LOCATION
11q14.3
LOCUSID
ALIAS
GCPIII,GPCIII,NAADALASE2,NAALADASE2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10003
MIM: 611636
HGNC: 14526
Ensembl: ENSG00000077616
Variants:
dbSNP: 10003
ClinVar: 10003
TCGA: ENSG00000077616
COSMIC: NAALAD2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Metabolism of amino acids and derivatives | REACTOME | R-HSA-71291 |
| Amino acid synthesis and interconversion (transamination) | REACTOME | R-HSA-70614 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34850884 | 2022 | Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus. | 1 |
| 34850884 | 2022 | Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus. | 1 |
| 34198725 | 2021 | Promoter Methylation of PRKCB, ADAMTS12, and NAALAD2 Is Specific to Prostate Cancer and Predicts Biochemical Disease Recurrence. | 9 |
| 34198725 | 2021 | Promoter Methylation of PRKCB, ADAMTS12, and NAALAD2 Is Specific to Prostate Cancer and Predicts Biochemical Disease Recurrence. | 9 |
| 30844704 | 2019 | GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond. | 6 |
| 30844704 | 2019 | GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond. | 6 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 11905994 | 2002 | Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II. | 37 |
| 12204797 | 2002 | Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk. | 12 |
| 11905994 | 2002 | Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II. | 37 |
| 12204797 | 2002 | Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk. | 12 |
Citation
Dessen P
NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41490/naalad2-(n-acetylated-alpha-linked-acidic-dipeptidase-2)
