Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
HSD48,NAC-alpha,NACA1,skNAC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4666
MIM: 601234
HGNC: 7629
Ensembl: ENSG00000196531
Variants:
dbSNP: 4666
ClinVar: 4666
TCGA: ENSG00000196531
COSMIC: NACA
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36219563 | 2022 | The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF-α. | 3 |
| 36219563 | 2022 | The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF-α. | 3 |
| 30948508 | 2019 | Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation. | 8 |
| 30982745 | 2019 | Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. | 17 |
| 30948508 | 2019 | Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation. | 8 |
| 30982745 | 2019 | Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. | 17 |
| 24901053 | 2014 | αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells. | 0 |
| 25209525 | 2014 | Overexpression of the skNAC gene in human rhabdomyosarcoma cells enhances their differentiation potential and inhibits tumor cell growth and spreading. | 2 |
| 24901053 | 2014 | αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells. | 0 |
| 25209525 | 2014 | Overexpression of the skNAC gene in human rhabdomyosarcoma cells enhances their differentiation potential and inhibits tumor cell growth and spreading. | 2 |
| 21509594 | 2011 | Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. | 7 |
| 22082360 | 2011 | Combinatorial control of ATF4-dependent gene transcription in osteoblasts. | 6 |
| 21509594 | 2011 | Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. | 7 |
| 22082360 | 2011 | Combinatorial control of ATF4-dependent gene transcription in osteoblasts. | 6 |
| 20214399 | 2010 | The crystal structure of the human nascent polypeptide-associated complex domain reveals a nucleic acid-binding region on the NACA subunit . | 18 |
Citation
Dessen P
NACA (nascent polypeptide associated complex subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2004-03-01
Online version: http://atlasgeneticsoncology.org/gene/41491/naca-(nascent-polypeptide-associated-complex-subunit-alpha)
