NDST3 (N-deacetylase and N-sulfotransferase 3)

2003-05-01  

Identity

HGNC
NDST3
LOCATION
4q26
LOCUSID
9348
ALIAS
HSST3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9348
MIM: 603950
HGNC: 7682
Ensembl: ENSG00000164100

Variants:

dbSNP: 9348
ClinVar: 9348
TCGA: ENSG00000164100
COSMIC: NDST3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164100ENST00000296499O95803

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGko00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGhsa00534
Metabolic pathwaysKEGGhsa01100
Glycosaminoglycan biosynthesis, heparan sulfate backboneKEGGhsa_M00059
Glycosaminoglycan biosynthesis, heparan sulfate backboneKEGGM00059
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolismREACTOMER-HSA-1638091
HS-GAG biosynthesisREACTOMER-HSA-2022928

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
342845452021Hsa_circ_0001017 inhibits proliferation and metastasis via regulating the let-7g-3p/NDST3 axis in glioma.4
344353792021NDST3 deacetylates α-tubulin and suppresses V-ATPase assembly and lysosomal acidification.11
342845452021Hsa_circ_0001017 inhibits proliferation and metastasis via regulating the let-7g-3p/NDST3 axis in glioma.4
344353792021NDST3 deacetylates α-tubulin and suppresses V-ATPase assembly and lysosomal acidification.11
291405832018Association study of NDST3 gene for schizophrenia, bipolar disorder, major depressive disorder in the Han Chinese population.4
291405832018Association study of NDST3 gene for schizophrenia, bipolar disorder, major depressive disorder in the Han Chinese population.4
267314382016A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese.15
267314382016A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese.15
251395292014rs11098403 polymorphism near NDST3 is associated with a reduced risk of schizophrenia in a Han Chinese population.3
251395292014rs11098403 polymorphism near NDST3 is associated with a reduced risk of schizophrenia in a Han Chinese population.3
242533402013Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.53
242533402013Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.53
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205495152010Genome-wide searching of rare genetic variants in WTCCC data.31

Citation

Dessen P

NDST3 (N-deacetylase and N-sulfotransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41514/ndst3-(n-deacetylase-and-n-sulfotransferase-3)