Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10811
MIM: 611255
HGNC: 10668
Ensembl: ENSG00000188747
Variants:
dbSNP: 10811
ClinVar: 10811
TCGA: ENSG00000188747
COSMIC: NOXA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188747 | ENST00000341349 | Q86UR1 |
| ENSG00000188747 | ENST00000392815 | Q86UR1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32015503 | 2020 | MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. | 20 |
| 32094511 | 2020 | MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. | 20 |
| 32847975 | 2020 | The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA. | 2 |
| 32015503 | 2020 | MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. | 20 |
| 32094511 | 2020 | MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. | 20 |
| 32847975 | 2020 | The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA. | 2 |
| 31285435 | 2019 | Noxa mitochondrial targeting domain induces necrosis via VDAC2 and mitochondrial catastrophe. | 9 |
| 31727958 | 2019 | Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. | 28 |
| 31285435 | 2019 | Noxa mitochondrial targeting domain induces necrosis via VDAC2 and mitochondrial catastrophe. | 9 |
| 31727958 | 2019 | Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. | 28 |
| 29374147 | 2018 | Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells. | 15 |
| 29374147 | 2018 | Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells. | 15 |
| 28625920 | 2017 | C-terminal tail of NADPH oxidase organizer 1 (Noxo1) mediates interaction with NADPH oxidase activator (Noxa1) in the NOX1 complex. | 3 |
| 28625920 | 2017 | C-terminal tail of NADPH oxidase organizer 1 (Noxo1) mediates interaction with NADPH oxidase activator (Noxa1) in the NOX1 complex. | 3 |
| 23957209 | 2013 | Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1. | 9 |
Citation
Dessen P
NOXA1 (NADPH oxidase activator 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41563/noxa1-(nadph-oxidase-activator-1)
