Identity
HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
EAR-2,EAR2,ERBAL2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2063
MIM: 132880
HGNC: 7977
Ensembl: ENSG00000160113
Variants:
dbSNP: 2063
ClinVar: 2063
TCGA: ENSG00000160113
COSMIC: NR2F6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160113 | ENST00000291442 | P10588 |
| ENSG00000160113 | ENST00000291442 | F1D8R3 |
| ENSG00000160113 | ENST00000596878 | M0R175 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
| Nuclear Receptor transcription pathway | REACTOME | R-HSA-383280 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38551071 | 2024 | UPK3A(+) umbrella cell damage mediated by TLR3-NR2F6 triggers programmed destruction of urothelium in Hunner-type interstitial cystitis/painful bladder syndrome. | 0 |
| 38551071 | 2024 | UPK3A(+) umbrella cell damage mediated by TLR3-NR2F6 triggers programmed destruction of urothelium in Hunner-type interstitial cystitis/painful bladder syndrome. | 0 |
| 36884115 | 2023 | Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients. | 0 |
| 37575237 | 2023 | NR2F6, a new immune checkpoint that acts as a potential biomarker of immunosuppression and contributes to poor clinical outcome in human glioma. | 1 |
| 36884115 | 2023 | Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients. | 0 |
| 37575237 | 2023 | NR2F6, a new immune checkpoint that acts as a potential biomarker of immunosuppression and contributes to poor clinical outcome in human glioma. | 1 |
| 34304715 | 2021 | Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma. | 2 |
| 34472280 | 2021 | [The role of nuclear receptor transcription factor NR2F6 in tumor]. | 1 |
| 34304715 | 2021 | Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma. | 2 |
| 34472280 | 2021 | [The role of nuclear receptor transcription factor NR2F6 in tumor]. | 1 |
| 32203934 | 2020 | Regulation of docetaxel chemosensitivity by NR2F6 in breast cancer. | 7 |
| 32752295 | 2020 | NR2F6 as a Prognostic Biomarker in HNSCC. | 11 |
| 32203934 | 2020 | Regulation of docetaxel chemosensitivity by NR2F6 in breast cancer. | 7 |
| 32752295 | 2020 | NR2F6 as a Prognostic Biomarker in HNSCC. | 11 |
| 30895619 | 2019 | Nuclear orphan receptor NR2F6 confers cisplatin resistance in epithelial ovarian cancer cells by activating the Notch3 signaling pathway. | 20 |
Citation
Dessen P
NR2F6 (nuclear receptor subfamily 2 group F member 6)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41572/nr2f6-(nuclear-receptor-subfamily-2-group-f-member-6)
