TENM4 (teneurin transmembrane protein 4)

2003-12-01   Dessen P  

Identity

HGNC
TENM4
LOCATION
11q14.1
LOCUSID
26011
ALIAS
Doc4,ETM5,ODZ4,TEN4,TNM4,Ten-M4,ten-4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26011
MIM: 610084
HGNC: 29945
Ensembl: ENSG00000149256

Variants:

dbSNP: 26011
ClinVar: 26011
TCGA: ENSG00000149256
COSMIC: TENM4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149256ENST00000278550Q6N022
ENSG00000149256ENST00000530738H0YCJ4
ENSG00000149256ENST00000533074E9PPG4
ENSG00000149256ENST00000533525H0YCW4

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366890092023Han family with essential tremor caused by the P421L variant of the TENM4 gene in China.0
366890092023Han family with essential tremor caused by the P421L variant of the TENM4 gene in China.0
281589092017Teneurin transmembrane protein 4 is not a cause for essential tremor in a Canadian population.8
281589092017Teneurin transmembrane protein 4 is not a cause for essential tremor in a Canadian population.8
275698442016Essential tremor linked TENM4 mutation found in healthy Chinese individuals.9
275698442016Essential tremor linked TENM4 mutation found in healthy Chinese individuals.9
261880062015Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor.61
261880062015Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor.61
246483132014Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation.14
246483132014Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation.14
236115372013The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing.15
239910582013Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.25
236115372013The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing.15
239910582013Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.25
219269722011Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.697

Citation

Dessen P

TENM4 (teneurin transmembrane protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41605/tenm4-(teneurin-transmembrane-protein-4)