Identity
HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
HMMH,HOGG1,MUTM,OGH1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4968
MIM: 601982
HGNC: 8125
Ensembl: ENSG00000114026
Variants:
dbSNP: 4968
ClinVar: 4968
TCGA: ENSG00000114026
COSMIC: OGG1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | VariantAnnotation | not associated | PD | 28796378 | |
| PA164713176 | Platinum compounds | Chemical | VariantAnnotation | not associated | PD | 28796378 | |
| PA166122986 | radiotherapy | Chemical | VariantAnnotation | not associated | PD | 28796378 | |
| PA445742 | Stomach Neoplasms | Disease | VariantAnnotation | not associated | PD | 28796378 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37991642 | 2024 | The 24-h profile of the DNA repair enzyme 8-oxoguanine glycosylase 1 (OGG1) is associated with age, TNF-α, and waist circumference in healthy adults. | 0 |
| 38236479 | 2024 | Investigation of APE1 and OGG1 expression in chronic hemodialysis patients. | 0 |
| 38237481 | 2024 | Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1. | 0 |
| 38334141 | 2024 | Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease. | 0 |
| 38363604 | 2024 | OGG1 prevents atherosclerosis-induced vascular endothelial cell injury through mediating DNA damage repair. | 0 |
| 38554113 | 2024 | SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner. | 0 |
| 37991642 | 2024 | The 24-h profile of the DNA repair enzyme 8-oxoguanine glycosylase 1 (OGG1) is associated with age, TNF-α, and waist circumference in healthy adults. | 0 |
| 38236479 | 2024 | Investigation of APE1 and OGG1 expression in chronic hemodialysis patients. | 0 |
| 38237481 | 2024 | Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1. | 0 |
| 38334141 | 2024 | Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease. | 0 |
| 38363604 | 2024 | OGG1 prevents atherosclerosis-induced vascular endothelial cell injury through mediating DNA damage repair. | 0 |
| 38554113 | 2024 | SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner. | 0 |
| 36472850 | 2023 | PARP1 and OGG1 in Medicated Patients With Depression and the Response to ECT. | 0 |
| 36528059 | 2023 | Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine. | 5 |
| 36982562 | 2023 | 8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer. | 1 |
Citation
Dessen P
OGG1 (8-oxoguanine DNA glycosylase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41606/ogg1-(8-oxoguanine-dna-glycosylase)
