Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9943
MIM: 604046
HGNC: 8508
Ensembl: ENSG00000172939
Variants:
dbSNP: 9943
ClinVar: 9943
TCGA: ENSG00000172939
COSMIC: OXSR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172939 | ENST00000311806 | O95747 |
| ENSG00000172939 | ENST00000311806 | A0A024R2M7 |
| ENSG00000172939 | ENST00000426620 | F8WBK9 |
| ENSG00000172939 | ENST00000446845 | C9JIG9 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA320 | SLC12A1 | Gene | Pathway | associated | 23788015 | ||
| PA38243 | STK39 | Gene | Pathway | associated | 23788015 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34726826 | 2022 | Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains. | 1 |
| 34983467 | 2022 | Association of genetic variants of oxidative stress responsive kinase 1 (OXSR1) with asthma exacerbations in non-smoking asthmatics. | 3 |
| 34726826 | 2022 | Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains. | 1 |
| 34983467 | 2022 | Association of genetic variants of oxidative stress responsive kinase 1 (OXSR1) with asthma exacerbations in non-smoking asthmatics. | 3 |
| 31020807 | 2020 | Association of OSR-1 With Vascular Dysfunction and Hypertension in Polycystic Kidney Disease. | 1 |
| 31614064 | 2020 | The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner. | 9 |
| 32424721 | 2020 | High expression of OSR1 as a predictive biomarker for poor prognosis and lymph node metastasis in breast cancer. | 7 |
| 32828531 | 2020 | SPAK and OSR1 kinases bind and phosphorylate the β(2)-Adrenergic receptor. | 1 |
| 31020807 | 2020 | Association of OSR-1 With Vascular Dysfunction and Hypertension in Polycystic Kidney Disease. | 1 |
| 31614064 | 2020 | The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner. | 9 |
| 32424721 | 2020 | High expression of OSR1 as a predictive biomarker for poor prognosis and lymph node metastasis in breast cancer. | 7 |
| 32828531 | 2020 | SPAK and OSR1 kinases bind and phosphorylate the β(2)-Adrenergic receptor. | 1 |
| 30894278 | 2019 | Sequence specific assignment and determination of OSR1 C-terminal domain structure by NMR. | 1 |
| 30894278 | 2019 | Sequence specific assignment and determination of OSR1 C-terminal domain structure by NMR. | 1 |
| 30054970 | 2018 | Circulating Candidate Biomarkers in Giant Cell Tumors of Bone. | 1 |
Citation
Dessen P
OXSR1 (oxidative stress responsive kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41617/oxsr1-(oxidative-stress-responsive-kinase-1)
