Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26471
MIM: 614812
HGNC: 29990
Ensembl: ENSG00000176046
Variants:
dbSNP: 26471
ClinVar: 26471
TCGA: ENSG00000176046
COSMIC: NUPR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176046 | ENST00000324873 | O60356 |
| ENSG00000176046 | ENST00000324873 | A0A024QZC4 |
| ENSG00000176046 | ENST00000395641 | O60356 |
| ENSG00000176046 | ENST00000567646 | H3BS92 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transcriptional misregulation in cancer | KEGG | ko05202 |
| Transcriptional misregulation in cancer | KEGG | hsa05202 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37477758 | 2024 | WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion. | 2 |
| 38653091 | 2024 | NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway. | 0 |
| 37477758 | 2024 | WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion. | 2 |
| 38653091 | 2024 | NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway. | 0 |
| 36468653 | 2023 | NUPR1 imparts oncogenic potential in bladder cancer. | 7 |
| 37566478 | 2023 | Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis. | 0 |
| 37807730 | 2023 | [Mechanism of nuclear protein 1 in the resistance to axitinib in clear cell renal cell carcinoma]. | 0 |
| 37879429 | 2023 | SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest. | 0 |
| 36468653 | 2023 | NUPR1 imparts oncogenic potential in bladder cancer. | 7 |
| 37566478 | 2023 | Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis. | 0 |
| 37807730 | 2023 | [Mechanism of nuclear protein 1 in the resistance to axitinib in clear cell renal cell carcinoma]. | 0 |
| 37879429 | 2023 | SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest. | 0 |
| 35350907 | 2022 | Histone methyltransferase Dot1L inhibits pancreatic cancer cell apoptosis by promoting NUPR1 expression. | 3 |
| 35462576 | 2022 | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy. | 24 |
| 35660538 | 2022 | NUPR1 promotes the proliferation and migration of breast cancer cells by activating TFE3 transcription to induce autophagy. | 9 |
Citation
Dessen P
NUPR1 (nuclear protein 1, transcriptional regulator)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41627/nupr1-(nuclear-protein-1-transcriptional-regulator)
