Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
G17,HOX12,PBX2MHC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5089
MIM: 176311
HGNC: 8633
Ensembl: ENSG00000204304
Variants:
dbSNP: 5089
ClinVar: 5089
TCGA: ENSG00000204304
COSMIC: PBX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204304 | ENST00000375050 | P40425 |
| ENSG00000204304 | ENST00000375050 | A0A024RCR3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33535170 | 2021 | Coexpression of HOXA6 and PBX2 promotes metastasis in gastric cancer. | 7 |
| 33535170 | 2021 | Coexpression of HOXA6 and PBX2 promotes metastasis in gastric cancer. | 7 |
| 26572100 | 2016 | MicroRNA‑1915‑3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2. | 8 |
| 26852910 | 2016 | Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects. | 4 |
| 26572100 | 2016 | MicroRNA‑1915‑3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2. | 8 |
| 26852910 | 2016 | Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects. | 4 |
| 23400877 | 2013 | The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway. | 32 |
| 23400877 | 2013 | The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway. | 32 |
| 22374608 | 2012 | Expression level of pre-B-cell leukemia transcription factor 2 (PBX2) as a prognostic marker for gingival squamous cell carcinoma. | 5 |
| 22374608 | 2012 | Expression level of pre-B-cell leukemia transcription factor 2 (PBX2) as a prognostic marker for gingival squamous cell carcinoma. | 5 |
| 20126986 | 2010 | Expression level of Pre B cell leukemia homeobox 2 correlates with poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma. | 7 |
| 20416077 | 2010 | Identification of type 2 diabetes-associated combination of SNPs using support vector machine. | 31 |
| 20587610 | 2010 | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. | 3 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20126986 | 2010 | Expression level of Pre B cell leukemia homeobox 2 correlates with poor prognosis of gastric adenocarcinoma and esophageal squamous cell carcinoma. | 7 |
Citation
Dessen P
PBX2 (PBX homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41647/pbx2-(pbx-homeobox-2)
