Identity
HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
IPCA-7,IPCA7,PCANAP7,SYT-VII,SYTVII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9066
MIM: 604146
HGNC: 11514
Ensembl: ENSG00000011347
Variants:
dbSNP: 9066
ClinVar: 9066
TCGA: ENSG00000011347
COSMIC: SYT7
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Protein-protein interactions at synapses | REACTOME | R-HSA-6794362 |
| Interactions of neurexins and neuroligins at synapses | REACTOME | R-HSA-6794361 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37774826 | 2023 | SYT7 is a key player in increasing exosome secretion and promoting angiogenesis in non-small-cell lung cancer. | 2 |
| 37774826 | 2023 | SYT7 is a key player in increasing exosome secretion and promoting angiogenesis in non-small-cell lung cancer. | 2 |
| 35073278 | 2022 | SYT7 plays a role in promoting thyroid cancer by mediating HMGB3 ubiquitination. | 5 |
| 35073278 | 2022 | SYT7 plays a role in promoting thyroid cancer by mediating HMGB3 ubiquitination. | 5 |
| 31631310 | 2020 | Silencing of synaptotagmin 7 regulates osteosarcoma cell proliferation, apoptosis, and migration. | 4 |
| 32041882 | 2020 | Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. | 12 |
| 32825966 | 2020 | High SYT7 expression is associated with poor prognosis in human non-small cell lung carcinoma. | 3 |
| 33052751 | 2020 | Syt-7 overexpression predicts poor prognosis and promotes cell proliferation in hepatocellular carcinoma. | 2 |
| 33229564 | 2020 | Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. | 7 |
| 31631310 | 2020 | Silencing of synaptotagmin 7 regulates osteosarcoma cell proliferation, apoptosis, and migration. | 4 |
| 32041882 | 2020 | Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. | 12 |
| 32825966 | 2020 | High SYT7 expression is associated with poor prognosis in human non-small cell lung carcinoma. | 3 |
| 33052751 | 2020 | Syt-7 overexpression predicts poor prognosis and promotes cell proliferation in hepatocellular carcinoma. | 2 |
| 33229564 | 2020 | Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. | 7 |
| 30647108 | 2019 | Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. | 5 |
Citation
Dessen P
SYT7 (synaptotagmin 7)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41658/syt7-(synaptotagmin-7)
