Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5133
MIM: 600244
HGNC: 8760
Ensembl: ENSG00000188389
Variants:
dbSNP: 5133
ClinVar: 5133
TCGA: ENSG00000188389
COSMIC: PDCD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188389 | ENST00000334409 | Q15116 |
| ENSG00000188389 | ENST00000334409 | A0A0M3M0G7 |
| ENSG00000188389 | ENST00000343705 | H0Y2W6 |
| ENSG00000188389 | ENST00000418831 | E7ER21 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37419794 | 2024 | The association between PD-1 / PD-L1 expression and clinicopathological features in sarcomatoid renal cell carcinoma. | 0 |
| 37553821 | 2024 | Apoptotic bodies inhibit inflammation by PDL1-PD1-mediated macrophage metabolic reprogramming. | 2 |
| 37688463 | 2024 | Elevated programmed cell death-1 protein/ligand (PD-1/PD-L1) and variants are associated with susceptibility to multiple myeloma: a case-control study in the Chinese cohort. | 0 |
| 37733830 | 2024 | PD-1 Blockade Induces Reactivation of Nonproductive T-Cell Responses Characterized by NF-κB Signaling in Patients with Pancreatic Cancer. | 2 |
| 38043270 | 2024 | An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3. | 0 |
| 38142184 | 2024 | Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women. | 0 |
| 38154265 | 2024 | The multiple arrays of a PD1-derived peptide on chromatin specifically bind to PD-L1 and induce doxorubicin resistance in cancer cell lines. | 0 |
| 38167274 | 2024 | Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1. | 1 |
| 38171036 | 2024 | Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma. | 0 |
| 38175205 | 2024 | Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression. | 0 |
| 38229027 | 2024 | Negative prognostic behaviour of PD-L1 expression in tongue and larynx squamous cell carcinoma and its significant predictive power in combination with PD-1 expression on TILs. | 0 |
| 38241371 | 2024 | Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling. | 1 |
| 38273364 | 2024 | IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway. | 1 |
| 38378036 | 2024 | The prognostic significance of programmed cell death protein 1 and its ligand on lymphoma cells and tumor-immune cells in diffuse large B-cell lymphoma, not otherwise specified. | 0 |
| 38424104 | 2024 | IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway. | 0 |
Citation
Dessen P
PDCD1 (programmed cell death 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41673/pdcd1-(programmed-cell-death-1)
