Identity
HGNC
LOCATION
6q27
LOCUSID
ALIAS
ADSD2,HSPDE10A,IOLOD,LINC00473,PDE10A19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10846
MIM: 610652
HGNC: 8772
Ensembl: ENSG00000112541
Variants:
dbSNP: 10846
ClinVar: 10846
TCGA: ENSG00000112541
COSMIC: PDE10A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36805523 | 2023 | Expanding the genotype-phenotype landscape of PDE10A-associated movement disorders. | 0 |
| 36805523 | 2023 | Expanding the genotype-phenotype landscape of PDE10A-associated movement disorders. | 0 |
| 34550322 | 2022 | Role of PDE10A in vascular smooth muscle cell hyperplasia and pathological vascular remodelling. | 2 |
| 36324187 | 2022 | Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer. | 7 |
| 34550322 | 2022 | Role of PDE10A in vascular smooth muscle cell hyperplasia and pathological vascular remodelling. | 2 |
| 36324187 | 2022 | Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer. | 7 |
| 33908139 | 2021 | LINC00473 downregulation facilitates trophoblast cell migration and invasion via the miR-15a-5p/LITAF axis in pre-eclampsia. | 9 |
| 33914237 | 2021 | Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons. | 8 |
| 33908139 | 2021 | LINC00473 downregulation facilitates trophoblast cell migration and invasion via the miR-15a-5p/LITAF axis in pre-eclampsia. | 9 |
| 33914237 | 2021 | Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons. | 8 |
| 31871190 | 2020 | Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme. | 4 |
| 32119913 | 2020 | Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease. | 9 |
| 31871190 | 2020 | Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme. | 4 |
| 32119913 | 2020 | Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease. | 9 |
| 31315972 | 2019 | Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity. | 27 |
Citation
Dessen P
PDE10A (phosphodiesterase 10A)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41678/pde10a-(phosphodiesterase-10a)
