Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
HEL-215,HEL-S-54e,PHB1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5245
MIM: 176705
HGNC: 8912
Ensembl: ENSG00000167085
Variants:
dbSNP: 5245
ClinVar: 5245
TCGA: ENSG00000167085
COSMIC: PHB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38086446 | 2024 | Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis. | 1 |
| 38617530 | 2024 | PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer. | 0 |
| 38086446 | 2024 | Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis. | 1 |
| 38617530 | 2024 | PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer. | 0 |
| 36346305 | 2023 | XIAP and PHB1 Regulate Anoikis through Competitive Binding to TRAF6. | 1 |
| 37359543 | 2023 | The landscape of mitophagy in sepsis reveals PHB1 as an NLRP3 inflammasome inhibitor. | 2 |
| 37373067 | 2023 | Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells. | 1 |
| 38332916 | 2023 | Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids. | 0 |
| 36346305 | 2023 | XIAP and PHB1 Regulate Anoikis through Competitive Binding to TRAF6. | 1 |
| 37359543 | 2023 | The landscape of mitophagy in sepsis reveals PHB1 as an NLRP3 inflammasome inhibitor. | 2 |
| 37373067 | 2023 | Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells. | 1 |
| 38332916 | 2023 | Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids. | 0 |
| 35639746 | 2022 | Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis. | 3 |
| 35639746 | 2022 | Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis. | 3 |
| 33259040 | 2021 | Prohibitin regulates mTOR pathway via interaction with FKBP8. | 6 |
Citation
Dessen P
PHB (prohibitin)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41701/phb-(prohibitin)
